MySQL 8.0

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select version();

version()

8.0.36

CREATE TABLE foo (
  b BINARY(16)  DEFAULT (UUID_TO_BIN(UUID()))
);
INSERT INTO foo () VALUES();
INSERT INTO foo () VALUES(DEFAULT);
SELECT BIN_TO_UUID(b) FROM foo;

BIN_TO_UUID(b)

2683d289-5fad-11ef-9333-5dd61c05c5cf

26841b2c-5fad-11ef-9333-5dd61c05c5cf